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New Method Holds Promise for HIV Vaccine Development

April 16, 2015

NEW YORK – An IAVI-led team of scientists has defined an additional way to generate trimers from the major HIV subtypes A, B and C, with scalable properties that could benefit future clinical development of HIV vaccine candidates designed to elicit broadly neutralizing antibodies. The trimer is the critical target on the surface of HIV…

Scientific Publications

Immunogenetic influences on acquisition of HIV 1 infection consensus findings from two African cohorts point to an enhancer element in IL19 1q32 2

Scientific Publications

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV 1 drug resistance an individual patient and sequence level meta analysis

Scientific Publications

Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose

Scientific Publications

An efficiently cleaved HIV 1 clade C Env selectively binds to neutralizing antibodies

Scientific Publications

Comprehensive antigenic map of a cleaved soluble HIV 1 envelope trimer

Scientific Publications

Replicative fitness of transmitted HIV 1 drives acute immune activation proviral load in memory CD4 T cells and disease progression

Press Releases

Margie McGlynn to Step Down as President and CEO; Search for Successor Underway

March 17, 2015

NEW YORK – Margaret McGlynn will step down after four years as President and CEO of the International AIDS Vaccine Initiative (IAVI). A search for her successor is underway, led by IAVI’s Board of Directors. “Margie’s outstanding experience as head of Merck global vaccines and her unique blend of professionalism and dedication have strongly positioned…

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New Method Holds Promise for HIV Vaccine Development

Immunogenetic influences on acquisition of HIV 1 infection consensus findings from two African cohorts point to an enhancer element in IL19 1q32 2

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV 1 drug resistance an individual patient and sequence level meta analysis

Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose

An efficiently cleaved HIV 1 clade C Env selectively binds to neutralizing antibodies

Comprehensive antigenic map of a cleaved soluble HIV 1 envelope trimer

Replicative fitness of transmitted HIV 1 drives acute immune activation proviral load in memory CD4 T cells and disease progression

Margie McGlynn to Step Down as President and CEO; Search for Successor Underway

Media & Resources

Filter by

Type

Health area

Location

Topic

Year

Journal

Publication

Fact sheet & publication type

New Method Holds Promise for HIV Vaccine Development

Immunogenetic influences on acquisition of HIV 1 infection consensus findings from two African cohorts point to an enhancer element in IL19 1q32 2

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV 1 drug resistance an individual patient and sequence level meta analysis

Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose

An efficiently cleaved HIV 1 clade C Env selectively binds to neutralizing antibodies

Comprehensive antigenic map of a cleaved soluble HIV 1 envelope trimer

Replicative fitness of transmitted HIV 1 drives acute immune activation proviral load in memory CD4 T cells and disease progression

Margie McGlynn to Step Down as President and CEO; Search for Successor Underway

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