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Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

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New HIV-Mimicking Particles That Trigger Immune Response Could Advance AIDS Vaccine Design

May 19, 2016

Call it a sheep in wolf’s clothing. Researchers with the International Aids Vaccine Initiative (IAVI) and The Scripps Research Institute (TSRI) have built tiny particles that resemble HIV on their outside and used them to provoke an immune response in animals. Their work, which was published today in the journal Cell Reports, could advance the…

Press Releases

Insights into the Development of Antibodies That Target a Large Portion of HIV Strains Could Advance Vaccine Design

May 17, 2016

A sub-Saharan African donor’s blood has yielded remarkable finds that could be crucial in the search for an AIDS vaccine. An infected donor’s immune system naturally made potent antibodies, which lab tests showed could effectively recognize and neutralize about 50 percent of all HIV-1 strains circulating around the world. HIV-1 is the most widespread HIV…

Scientific Publications

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV 1 Neutralization Targeting the Env High Mannose Patch

Scientific Publications

Fusion peptide of HIV 1 as a site of vulnerability to neutralizing antibody

Scientific Publications

Trimeric HIV 1 Env Structures Define Glycan Shields from Clades A B and G

Scientific Publications

High Resolution Longitudinal Study of HIV 1 Env Vaccine Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Scientific Publications

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01 Class Antibodies in an HIV 1 Infected Chinese Donor

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Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

New HIV-Mimicking Particles That Trigger Immune Response Could Advance AIDS Vaccine Design

Insights into the Development of Antibodies That Target a Large Portion of HIV Strains Could Advance Vaccine Design

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV 1 Neutralization Targeting the Env High Mannose Patch

Fusion peptide of HIV 1 as a site of vulnerability to neutralizing antibody

Trimeric HIV 1 Env Structures Define Glycan Shields from Clades A B and G

High Resolution Longitudinal Study of HIV 1 Env Vaccine Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01 Class Antibodies in an HIV 1 Infected Chinese Donor

Media & Resources

Filter by

Type

Health area

Location

Topic

Year

Journal

Publication

Fact sheet & publication type

Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

New HIV-Mimicking Particles That Trigger Immune Response Could Advance AIDS Vaccine Design

Insights into the Development of Antibodies That Target a Large Portion of HIV Strains Could Advance Vaccine Design

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV 1 Neutralization Targeting the Env High Mannose Patch

Fusion peptide of HIV 1 as a site of vulnerability to neutralizing antibody

Trimeric HIV 1 Env Structures Define Glycan Shields from Clades A B and G

High Resolution Longitudinal Study of HIV 1 Env Vaccine Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01 Class Antibodies in an HIV 1 Infected Chinese Donor

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